A small town doctor (Jean Hersholt) turns his concern towards the plight of Bob Webster (Barton Yarborough), a lowly bank clerk accused of stealing three thousand dollars. Tragically widowed, Bob is now the sole parent to little musical protege Jane (Anne Bennett). Unable to cope with the recent death of her mother and now faced with a long separation from her father, the little girl's chances of musical theater glory are surely dashed unless Dr. Christian can prove his hunch to the Governor (Neil Hamilton) that a grave miscarriage of justice has taken place in the small town of River's End.
They Meet Again is the sixth and final entry in RKO's Dr. Christian series.